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Adjective: up the duff
Usage: Brit, informal
  1. Carrying developing offspring within the body or being about to produce new life
    "You mean maybe she's up the duff?";
    - pregnant, up the spout [informal], preggo [Austral, NZ, informal], preggers [informal], up the stick [Brit, informal]

See also: big, enceinte [archaic], expectant, gravid [technical], great, heavy, large, with child [archaic]

Encyclopedia: Up the duff