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1. An effortful attempt to attain a goal
   - striving, nisus, strain

1. A symptom of some physical hurt or disorder
   "the patient developed severe pain and distension";
   - hurting
    
2. Emotional distress; a fundamental feeling that people try to avoid
   "the pain of loneliness";
   - painfulness
    
3. A somatic sensation of acute discomfort
   "as the intensity increased the sensation changed from tickle to pain";
   - pain sensation, painful sensation
    
4. A bothersome annoying person
   "that kid is a terrible pain";
   - pain in the neck [informal], nuisance
    
5. Something or someone that causes annoyance, inconvenience, or makes life more difficult
   "a bit of a pain";
   - annoyance, bother, botheration [informal], infliction, pain in the neck [informal], irritation, nuisance

1. Cause bodily suffering to and make sick or indisposed
   - trouble, ail
    
2. Cause emotional anguish or make miserable
   "It pains me to see my children not being taught well in school";
   - anguish, hurt

Sounds like: pain, pains

Type of: attempt, disagreeable person, discomfit, discompose, disconcert, effort, endeavor [US], endeavour [Brit, Cdn], feeling, hurt, negative stimulus, somaesthesia [Brit, Cdn], somatesthesia, somatic sensation, somesthesia [N. Amer], symptom, try, unpleasant person, untune, upset

Antonym: pleasance

Encyclopedia: Pains, district of Santa Maria