1. Having self-possession upset; thrown into confusion
   "the hecklers pelted the discombobulated speaker with anything that came to hand";
   - disconcerted, thrown, rattled [informal]

1. Confuse or disorient completely
   "The plot twist completely discombobulated the audience";
   - bewilder, bemuse, throw
    
2. Confuse or leave at a loss because of something complex or difficult to understand
   "These questions discombobulate even the experts";
   - confuse, throw, fox, befuddle, fuddle, bedevil, confound, perplex, vex, stick, get, puzzle, mystify, baffle, beat, pose, bewilder, flummox, stupefy, nonplus, gravel, dumbfound

See also: discomposed

Type of: affect, bear on, bear upon, discomfit, discompose, disconcert, impact, untune [rare], upset