WordWeb Online

1. Move away from a place into another direction
   "The train departs at noon";
   - go, go away
    
2. Be at variance with; be out of line with
   - deviate, vary, diverge
    
3. Head for somewhere else
   "The family departed for Florida";
   - part, start, start out, set forth, set off, set out, take off
    
4. Go away or leave
   - take leave, quit
    
5. Remove oneself from an association with or participation in
   "She wants to depart";
   - leave, pull up stakes
    
6. Wander from a direct or straight course
   - sidetrack, digress, straggle

Derived forms: departs, departing, departed

Type of: change, deviate, differ, divert, exit, get out, go away, go forth, go out, leave, off [informal]

Antonym: conform, stay