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1. Take the first step or steps in carrying out an action
   - get down, begin, get, start, set about, set out, commence
    
2. Head for somewhere else
   "The family started out for Florida";
   - depart, part, start, set forth, set off, set out, take off

Derived forms: starts out, started out, starting out

Type of: go away, go forth, leave, off [informal]

Antonym: end