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Adjective: splenetic  spli'ne-tik
  1. Of or relating to the spleen
    "The doctor examined the patient's splenetic function";
    - splenic, lienal
     
  2. Very irritable
    "splenetic exchanges between the White House and the press";
    - bristly, prickly, waspish, spiky

See also: ill-natured

Encyclopedia: Splenetic