1. Defeat soundly and humiliatingly
   "The home team spiflicated the visitors";
   - demolish [informal], destroy, spifflicate [Brit, informal], pulverize [Brit, informal], pulverise [Brit, informal], annihilate [informal]
    
2. Completely eliminate or undo the existence of
   "The fire spiflicated the house";
   - destroy, destruct, spifflicate [Brit, informal], uncreate [literary]

Derived forms: spiflicated, spiflicates, spiflicating

Type of: defeat, get the better of, overcome, undo, unmake