WordWeb Online

1. Deprived of sexual capacity or sexual attributes
   "The unsexed animals were treated for 14 days with antibiotics";
   - castrated

1. Deprive of sex or sexual powers
    
2. Remove the qualities typical of one's sex
   "She unsexed herself"
    
3. Make infertile
   - sterilize, sterilise [Brit], desex, desexualize, desexualise [Brit], fix

See also: altered, cut, emasculated, gelded, neutered, spayed

Type of: alter, change, deprive, divest, modify, operate, operate on, strip

Antonym: uncastrated