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1. Affording physical relief
   "a soothing ointment for her sunburn"
    
2. Freeing from fear and anxiety
   - assuasive

1. Give moral or emotional strength to
   - comfort, console, solace
    
2. Cause to feel better
   "the medicine soothes the pain of the inflammation"

See also: comfortable, comfy, reassuring

Type of: alleviate, assuage, palliate, relieve

Antonym: irritate

Encyclopedia: Soothe