1. A congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
   "The infant was diagnosed with severe combined immunodeficiency through newborn screening";
   - severe combined immunodeficiency disease, SCID

Type of: immunodeficiency, monogenic disease, monogenic disorder

Encyclopedia: Severe combined immunodeficiency