1. Doubt about the truth of something
   "He raised an eyebrow in scepticism at her far-fetched story";
   - incredulity, disbelief, skepticism [N. Amer], mental rejection
    
2. The disbelief in any claims of ultimate knowledge
   "The scientist's scepticism drove her to rigorously test each hypothesis"; "The philosopher's scepticism challenged accepted truths";
   - agnosticism, skepticism [N. Amer]

Derived forms: scepticisms

Type of: disbelief, doubt, doubtfulness, dubiety, dubiousness, incertitude, unbelief, uncertainty

Encyclopedia: Scepticism