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Adjective: pestilent  pe-stu-lunt
  1. Likely to spread and cause an epidemic disease
    "The pestilent rats carried fleas that spread the plague";
    - pestilential, pestiferous, plaguey
     
  2. Exceedingly harmful
    "The pestilent disease decimated the population";
    - baneful [archaic], deadly, pernicious

See also: epidemic, noxious