1. Congenital condition in which the colon does not have the normal network of nerves; there is little urge to defecate so the faeces accumulate and cause megacolon
   "The infant was diagnosed with Hirschsprung's disease after showing severe constipation";
   - congenital megacolon

Type of: genetic abnormality, genetic defect, genetic disease, genetic disorder, hereditary condition, hereditary disease, inherited disease, inherited disorder

Encyclopedia: Hirschsprung's disease