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Adjective: heartsore  'haa(r)t,sor
  1. Without or almost without hope
    "heartsore about his failure";
    - despondent, heartsick
     
  2. Full of sorrow
    "I hear from many heartsore people who are suffering from a great variety of losses";
    - brokenhearted, heartbroken, heartsick
Noun: heartsore  'haa(r)t,sor
Usage: rare
  1. Something that causes emotional pain or distress
    "The ongoing conflict is a heartsore issue for the community"

See also: hopeless, sorrowful