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Adjective: epochal  e-pu-kul
  1. Highly significant or important especially bringing about or marking the beginning of a new development or era
    "epochal decisions made by Roosevelt and Churchill";
    - epoch-making

See also: important, significant

Nearest

epitope
epitrochoidal engine
epixylon
epizeuxis
epizoan
epizoic
epizoon
epizootic
EPO
epoch
epochal
epoch-making
epode
Epona
eponym
eponymic
eponymous
eponymy
epos
epoxy
epoxy glue