1. Thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs
   "amyotrophic lateral sclerosis caused rapid deterioration of his muscle function";
   - ALS, Lou Gehrig's disease

Derived forms: amyotrophic lateral scleroses

Type of: induration, nervous disorder, neurological disease, neurological disorder, sclerosis

Encyclopedia: Amyotrophic lateral sclerosis, type 4