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Verb: acerbate  'a-su(r),beyt
  1. Cause to be bitter or resentful
    "These injustices acerbated her even more";
    - embitter, envenom [archaic]
     
  2. Make sour or bitter
    "The criticism acerbated his already foul mood"

Derived forms: acerbated, acerbates, acerbating

Type of: alter, cast down, change, deject, demoralise [Brit], demoralize, depress, dismay, dispirit, get down, modify